Does mutation affect the organism and its surroundings?

 


Introduction:

 

What is a mutation? How does mutation occur? Why do organisms get mutated? Can we treat mutation? Will we get enough rights if we are mutated?

 

           These are some of the many queries, which are asked by people. These people don’t stop until and unless they get the answer to their question, and I guess that their luck is shining bright today as all of their questions will be answered today through this writing. 

 

          To start with, let us know the meaning of the word ‘Mutation’. Online Cambridge dictionary (2019) refers to mutation as “the way in which genes change and produce permanent differences”. In simpler words, it is “a permanent change in an organism, or the changed organism itself”.

 

Description: 

 

 Any mutated organism is called a ‘Mutant’. Cambridge also says that a mutant is “an organism that is different from others of its type because of a permanent change in its genes”.   

 

         In the present era, mutants are going through a lot of hardships. They are secluded from the ‘normal’ society and are being discriminated against by other humans. They also lack some rights in a few of the 195 countries. People treat mutants, as though they are inferior to them, and they make them feel like they are very different from them. Now many mutants have gone into depression. 




Causes:

 

           Mutation can occur in any living organism; it can be a plant, or an animal, or also a human. The threat of mutation befalls on an organism when it’s original DNA (deoxyribonucleic acid) is changed or deleted by one of the following: 

 

1.     Error when the DNA is being replicated.

2.     The DNA can get deleted while it is being replicated from the parents to the offspring.

3.     If the person is exposed to a lot of chemicals, and radiation for a long period, the DNA of the person can get altered or get damaged.

If we sum up all the causes, then we can say that a mutation occurs when a DNA is altered by the means of deletion, insertion, transition or transversion. 

 

Consequences:

 

Mostly the mutation affects the organism’s health and development. The diseases caused by mutation are called ‘Genetic Disorder’. Base substitution mutation causes a genetic disorder called ‘sickle-cell disease’. Other mutations also cause ‘Cystic fibrosis’. Mutation in an organism: 

 

  • Prevents an embryo from surviving until its birth.
  • Cause protein in our body to malfunction or to disappear.
  • Can also, cause discrimination amongst people and the materialistic society.
  • Can kill an organism.
  • Can reduce the population of the country.

 

Going into depression are the people who are the target of mutation. They feel like they are not a part of our society. In some crucial cases, people suicide. Thus our world population reduces.

 

Although in some cases mutation can be a great help. A young woman in Scotland has been mutated, and the mutation causes her to feel virtually no pain. She feels very little anxiety and has enhanced wound healing in her due to the mutation. The research team is still working with her to invent new medicines for everyone to have this capability of healing very quickly. Imagine a world without pain. Amazing, right?

 

Global Perspective: 

Collins dictionary (2019) states that mutagen is “a substance or agent that can induce genetic mutation”. Mutagen can also be some type of radiation too. The examples of mutagens are:

1)     Ultraviolet rays

2)     Gamma radiation

3)     Free radicals

4)     Base analog chemicals

 

 In an online BBJR article (2017) the organization, WHO stated that it has requested “all the countries to update their data and reports on CF cases”. Many countries had not taken any action for this mutation, so WHO is persuading them to keep records and to consider these mutations too. WHO also hopes that the countries take some action to prevent these mutations within a couple of years and WHO is doing all in its power to prevent further mutations across the globe.

 

National Perspective:

          In the same article, (BBJR 2017 article), WHO also mentions that it has given nil financial support or sponsorship to any country. So for instance, if it is a very poor country, like some parts of Africa, then even though it wants to eradicate mutation, it can’t, as it doesn’t have the money to do it. There are many other factors that affect the way the countries react to this request (mentioned in global perspective); “civil war, poverty, malnutrition, and outbreaks of infectious diseases such as tuberculosis” and many more.

           The websites- https://www.ncbi.nlm.nih.gov/pubmed/15767750  and https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333734/  state that there is a lot of “genetic diversity among the Arabs” and many mutations in the “Mediterranean basin, throughout the Middle East, The Indian subcontinent, Southeast Asia, and Melanesia in to the Pacific Islands”. 

 

Source Evaluation:

All the websites which I used are trustworthy. Some websites are biased but the others are equally convincing. I have taken my information from non-biased government websites also. In the beginning, I was against mutated people, but after reading all these websites, especially https://ghr.nlm.nih.gov/primer/testing/discrimination, I came to know, that mutants are also like other people (sometimes better) who had mishaps in their lives and ended up to be mutated. I also realized that mutations need not always be a drawback. Sometimes, for people, the mutation is an asset. That’s how my perspective changed. 

 

The course of Action:

          We should stop genetic discrimination and consider them as our equal. They deserve enough rights as we do too. The government and the research team can work with mutants and devise some medicines and vaccines to cure and prevent further mutations in the future. The government should also consider these issues related to mutations in all countries.

 

Conclusion:

 So my conclusion is that mutation does affect the organism and its surroundings (the society) and it can be a good effect or a bad effect. Searching information about this has just made my perspective stronger and has made my belief of respecting and preventing mutation much stronger.

 

References:

·        https://dictionary.cambridge.org/dictionary/english/mutation

·        https://www.collinsdictionary.com/dictionary/english/mutagen

·        https://chem.libretexts.org/Courses/Eastern_Mennonite_University/EMU%3A_Chemistry_for_the_Life_Sciences_(Cessna)/19%3A_Nucleic_Acids/19.5%3A_Mutations_and_Genetic_Diseases

·        https://www.sciencedaily.com/releases/2019/03/190327203450.htm

·        http://www2.csudh.edu/nsturm/CHEMXL153/DNAMutationRepair.htm

·        https://ghr.nlm.nih.gov/primer/mutationsanddisorders/mutationscausedisease

·        http://www.bmbtrj.org/article.asp?issn=25889834;year=2017;volume=1;issue=2;spage=105;epage=112;aulast=Mirtajani

·        https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333734/

·        https://www.ncbi.nlm.nih.gov/pubmed/15767750

·        https://ghr.nlm.nih.gov/primer/testing/discrimination

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